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Pten Knockdown In Vivo Increases Excitatory Drive onto Dentate Granule Cells
Some cases of autism spectrum disorder have mutations in the lipid phosphatase, phosphatase and tensin homolog on chromosome 10 (Pten). Tissue specific deletion of Pten in the hippocampus and cortex of mice causes anatomical and behavioral abnormalities similar to human autism. However, the impact o...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3113533/ https://ncbi.nlm.nih.gov/pubmed/21411674 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0061-11.2011 |
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