Gastrointestinal Pathology in Juvenile and Adult CFTR-Knockout Ferrets

Cystic fibrosis (CF) is a multiorgan disease caused by loss of a functional cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel in many epithelia of the body. Here we report the pathology observed in the gastrointestinal organs of juvenile to adult CFTR-knockout ferrets. CF g...

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Main Authors: Sun, Xingshen, Olivier, Alicia K., Yi, Yaling, Pope, Christopher E., Hayden, Hillary S., Liang, Bo, Sui, Hongshu, Zhou, Weihong, Hager, Kyle R., Zhang, Yulong, Liu, Xiaoming, Yan, Ziying, Fisher, John T., Keiser, Nicholas W., Song, Yi, Tyler, Scott R., Goeken, J. Adam, Kinyon, Joann M., Radey, Matthew C., Fligg, Danielle, Wang, Xiaoyan, Xie, Weiliang, Lynch, Thomas J., Kaminsky, Paul M., Brittnacher, Mitchell J., Miller, Samuel I., Parekh, Kalpaj, Meyerholz, David K., Hoffman, Lucas R., Frana, Timothy, Stewart, Zoe A., Engelhardt, John F.
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2014
Subjects:
Regular Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4005986/
https://ncbi.nlm.nih.gov/pubmed/24637292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2014.01.035
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