Pancreatic and Islet Remodeling in Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Knockout Ferrets

In cystic fibrosis (CF), there is early destruction of the exocrine pancreas, and this results in a unique form of diabetes that affects approximately half of adult CF individuals. An animal model of cystic fibrosis–related diabetes has been developed in the ferret, which progresses through phases o...

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Bibliografske podrobnosti
izdano v:Am J Pathol
Main Authors: Rotti, Pavana G., Xie, Weiliang, Poudel, Ananta, Yi, Yaling, Sun, Xingshen, Tyler, Scott R., Uc, Aliye, Norris, Andrew W., Hara, Manami, Engelhardt, John F., Gibson-Corley, Katherine N.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2018
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5963477/
https://ncbi.nlm.nih.gov/pubmed/29366680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2017.12.015
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