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Infection Is Not Required for Mucoinflammatory Lung Disease in CFTR-Knockout Ferrets
Rationale: Classical interpretation of cystic fibrosis (CF) lung disease pathogenesis suggests that infection initiates disease progression, leading to an exuberant inflammatory response, excessive mucus, and ultimately bronchiectasis. Although symptomatic antibiotic treatment controls lung infectio...
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| Publicado no: | Am J Respir Crit Care Med |
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| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Thoracic Society
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5955060/ https://ncbi.nlm.nih.gov/pubmed/29327941 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201708-1616OC |
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