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Inhibitory Activity of Alkoxyalkyl and Alkyl Esters of Cidofovir and Cyclic Cidofovir against Orthopoxvirus Replication In Vitro

A new series of ether lipid esters of cidofovir (CDV) were evaluated against vaccinia and cowpox viruses. Activity was dependent on number of atoms in the alkyl or alkoxyalkyl chain, the linker moiety, and the presence of a double bond in the alkoxyalkyl chains linked to the phosphonate moiety of CD...

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Bibliografiset tiedot
Päätekijät: Keith, Kathy A., Wan, William B., Ciesla, Stephanie L., Beadle, James R., Hostetler, Karl Y., Kern, Earl R.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2004
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Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC400568/
https://ncbi.nlm.nih.gov/pubmed/15105146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.5.1869-1871.2004
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