Comparative Activities of Lipid Esters of Cidofovir and Cyclic Cidofovir against Replication of Herpesviruses In Vitro

Cidofovir (CDV) is an effective therapy for certain human cytomegalovirus (HCMV) infections in immunocompromised patients that are resistant to other antiviral drugs, but the compound is not active orally. To improve oral bioavailability, a series of lipid analogs of CDV and cyclic CDV (cCDV), inclu...

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Detalhes bibliográficos
Main Authors: Williams-Aziz, Stephanie L., Hartline, Caroll B., Harden, Emma A., Daily, Shannon L., Prichard, Mark N., Kushner, Nicole L., Beadle, James R., Wan, W. Brad, Hostetler, Karl Y., Kern, Earl R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1195409/
https://ncbi.nlm.nih.gov/pubmed/16127046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.9.3724-3733.2005
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