Comparative Activities of Lipid Esters of Cidofovir and Cyclic Cidofovir against Replication of Herpesviruses In Vitro

Cidofovir (CDV) is an effective therapy for certain human cytomegalovirus (HCMV) infections in immunocompromised patients that are resistant to other antiviral drugs, but the compound is not active orally. To improve oral bioavailability, a series of lipid analogs of CDV and cyclic CDV (cCDV), inclu...

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Autori principali: Williams-Aziz, Stephanie L., Hartline, Caroll B., Harden, Emma A., Daily, Shannon L., Prichard, Mark N., Kushner, Nicole L., Beadle, James R., Wan, W. Brad, Hostetler, Karl Y., Kern, Earl R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2005
Soggetti:
Antiviral Agents
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1195409/
https://ncbi.nlm.nih.gov/pubmed/16127046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.9.3724-3733.2005
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