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Impact of Mutations in the Coreceptor Binding Site on Human Immunodeficiency Virus Type 1 Fusion, Infection, and Entry Inhibitor Sensitivity

An increasingly large number of antiviral agents that prevent entry of human immunodeficiency virus (HIV) into cells are in preclinical and clinical development. The envelope (Env) protein of HIV is the major viral determinant that affects sensitivity to these compounds. To understand how changes in...

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Autors principals: Reeves, Jacqueline D., Miamidian, John L., Biscone, Mark J., Lee, Fang-Hua, Ahmad, Navid, Pierson, Theodore C., Doms, Robert W.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2004
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC400359/
https://ncbi.nlm.nih.gov/pubmed/15113926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.10.5476-5485.2004
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