Impact of Mutations in the Coreceptor Binding Site on Human Immunodeficiency Virus Type 1 Fusion, Infection, and Entry Inhibitor Sensitivity

An increasingly large number of antiviral agents that prevent entry of human immunodeficiency virus (HIV) into cells are in preclinical and clinical development. The envelope (Env) protein of HIV is the major viral determinant that affects sensitivity to these compounds. To understand how changes in...

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Detalles Bibliográficos
Autores principales: Reeves, Jacqueline D., Miamidian, John L., Biscone, Mark J., Lee, Fang-Hua, Ahmad, Navid, Pierson, Theodore C., Doms, Robert W.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2004
Materias:
Replication
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC400359/
https://ncbi.nlm.nih.gov/pubmed/15113926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.10.5476-5485.2004
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