Impact of Mutations in the Coreceptor Binding Site on Human Immunodeficiency Virus Type 1 Fusion, Infection, and Entry Inhibitor Sensitivity

An increasingly large number of antiviral agents that prevent entry of human immunodeficiency virus (HIV) into cells are in preclinical and clinical development. The envelope (Env) protein of HIV is the major viral determinant that affects sensitivity to these compounds. To understand how changes in...

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Detalhes bibliográficos
Main Authors: Reeves, Jacqueline D., Miamidian, John L., Biscone, Mark J., Lee, Fang-Hua, Ahmad, Navid, Pierson, Theodore C., Doms, Robert W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC400359/
https://ncbi.nlm.nih.gov/pubmed/15113926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.10.5476-5485.2004
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