Phosphorylation of the Antiviral Protein Interferon-inducible Transmembrane Protein 3 (IFITM3) Dually Regulates Its Endocytosis and Ubiquitination

Interferon-inducible transmembrane protein 3 (IFITM3) is essential for innate defense against influenza virus in mice and humans. IFITM3 localizes to endolysosomes where it prevents virus fusion, although mechanisms controlling its trafficking to this cellular compartment are not fully understood. W...

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Detaylı Bibliyografya
Asıl Yazarlar: Chesarino, Nicholas M., McMichael, Temet M., Hach, Jocelyn C., Yount, Jacob S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2014
Konular:
Immunology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002105/
https://ncbi.nlm.nih.gov/pubmed/24627473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.557694
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