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Palmitoylation on Conserved and Nonconserved Cysteines of Murine IFITM1 Regulates Its Stability and Anti-Influenza A Virus Activity

The interferon-induced transmembrane proteins (IFITMs) restrict infection by numerous viruses, yet the importance and regulation of individual isoforms remains unclear. Here, we report that murine IFITM1 (mIFITM1) is palmitoylated on one nonconserved cysteine and three conserved cysteines that are r...

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Detalhes bibliográficos
Main Authors: Hach, Jocelyn C., McMichael, Temet, Chesarino, Nicholas M., Yount, Jacob S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754091/
https://ncbi.nlm.nih.gov/pubmed/23804635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00621-13
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