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Regulation of the trafficking and antiviral activity of IFITM3 by post-translational modifications
IFITM3 restricts cellular infection by multiple important viral pathogens, and is particularly critical for the innate immune response against influenza virus. Expression of IFITM3 expands acidic endolysosomal compartments and prevents fusion of endocytosed viruses, leading to their degradation. Thi...
Sparad:
| I publikationen: | Future Microbiol |
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| Huvudupphovsmän: | , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2014
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4254935/ https://ncbi.nlm.nih.gov/pubmed/25405885 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/fmb.14.65 |
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