A direct role of Mad1 in the spindle assembly checkpoint beyond Mad2 kinetochore recruitment

The spindle assembly checkpoint (SAC) ensures accurate chromosome segregation by delaying entry into anaphase until all sister chromatids have become bi-oriented. A key component of the SAC is the Mad2 protein, which can adopt either an inactive open (O-Mad2) or active closed (C-Mad2) conformation....

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kruse, Thomas, Larsen, Marie Sofie Yoo, Sedgwick, Garry G, Sigurdsson, Jón Otti, Streicher, Werner, Olsen, Jesper V, Nilsson, Jakob
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Blackwell Publishing Ltd 2014
Pynciau:
Scientific Reports
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3989694/
https://ncbi.nlm.nih.gov/pubmed/24477933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/embr.201338101
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