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Mad1 kinetochore recruitment by Mps1-mediated phosphorylation of Bub1 signals the spindle checkpoint

The spindle checkpoint is a conserved signaling pathway that ensures genomic integrity by preventing cell division when chromosomes are not correctly attached to the spindle. Checkpoint activation depends on the hierarchical recruitment of checkpoint proteins to generate a catalytic platform at the...

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Detalhes bibliográficos
Main Authors: London, Nitobe, Biggins, Sue
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3909788/
https://ncbi.nlm.nih.gov/pubmed/24402315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.233700.113
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