The Bub1-TPR Domain Interacts Directly with Mad3 to Generate Robust Spindle Checkpoint Arrest

The spindle checkpoint monitors kinetochore-microtubule interactions and generates a “wait anaphase” delay when any defects are apparent [1, 2, 3]. This provides time for cells to correct chromosome attachment errors and ensure high-fidelity chromosome segregation. Checkpoint signals are generated a...

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Publicado no:Curr Biol
Main Authors: Leontiou, Ioanna, London, Nitobe, May, Karen M., Ma, Yingrui, Grzesiak, Lucile, Medina-Pritchard, Bethan, Amin, Priya, Jeyaprakash, A. Arockia, Biggins, Sue, Hardwick, Kevin G.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6657678/
https://ncbi.nlm.nih.gov/pubmed/31257143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2019.06.011
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