Conformation-specific anti-Mad2 monoclonal antibodies for the dissection of checkpoint signaling

The spindle assembly checkpoint (SAC) ensures accurate chromosome segregation during mitosis by delaying the activation of the anaphase-promoting complex/cyclosome (APC/C) in response to unattached kinetochores. The Mad2 protein is essential for a functional checkpoint because it binds directly to C...

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Detaylı Bibliyografya
Yayımlandı:MAbs
Asıl Yazarlar: Sedgwick, Garry G., Larsen, Marie Sofie Yoo, Lischetti, Tiziana, Streicher, Werner, Jersie-Christensen, Rosa Rakownikow, Olsen, Jesper V., Nilsson, Jakob
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Taylor & Francis 2016
Konular:
Report
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4966835/
https://ncbi.nlm.nih.gov/pubmed/26986935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2016.1160988
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