A carregar...
Stable MCC binding to the APC/C is required for a functional spindle assembly checkpoint
The spindle assembly checkpoint (SAC) delays progression into anaphase until all chromosomes have aligned on the metaphase plate by inhibiting Cdc20, the mitotic co-activator of the APC/C. Mad2 and BubR1 bind and inhibit Cdc20, thereby forming the mitotic checkpoint complex (MCC), which can bind sta...
Na minha lista:
| Main Authors: | , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Publishing Ltd
2014
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3989692/ https://ncbi.nlm.nih.gov/pubmed/24464857 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/embr.201337496 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|