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Cyclin A2 degradation during the spindle assembly checkpoint requires multiple binding modes to the APC/C
The anaphase-promoting complex/cyclosome (APC/C) orchestrates cell cycle progression by controlling the temporal degradation of specific cell cycle regulators. Although cyclin A2 and cyclin B1 are both targeted for degradation by the APC/C, during the spindle assembly checkpoint (SAC), the mitotic c...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6712056/ https://ncbi.nlm.nih.gov/pubmed/31455778 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11833-2 |
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