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Molecular basis of APC/C regulation by the spindle assembly checkpoint

In the dividing eukaryotic cell the spindle assembly checkpoint (SAC) ensures each daughter cell inherits an identical set of chromosomes. The SAC coordinates the correct attachment of sister chromatid kinetochores to the mitotic spindle with activation of the anaphase-promoting complex/cyclosome (A...

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Détails bibliographiques
Publié dans:Nature
Auteurs principaux: Alfieri, Claudio, Chang, Leifu, Zhang, Ziguo, Yang, Jing, Maslen, Sarah, Skehel, Mark, Barford, David
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5019344/
https://ncbi.nlm.nih.gov/pubmed/27509861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature19083
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