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Molecular mechanism of APC/C activation by mitotic phosphorylation
In eukaryotes, the anaphase-promoting complex/cyclosome (APC/C) regulates the ubiquitin-dependent proteolysis of specific cell cycle proteins to coordinate chromosome segregation in mitosis and entry into G1 (refs 1,2). The APC/C’s catalytic activity and ability to specify the destruction of particu...
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| Publicado en: | Nature |
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| Autores principales: | , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4878669/ https://ncbi.nlm.nih.gov/pubmed/27120157 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature17973 |
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