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Visualizing the complex functions and mechanisms of the anaphase promoting complex/cyclosome (APC/C)

The anaphase promoting complex or cyclosome (APC/C) is a large multi-subunit E3 ubiquitin ligase that orchestrates cell cycle progression by mediating the degradation of important cell cycle regulators. During the two decades since its discovery, much has been learnt concerning its role in recognizi...

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Detalhes bibliográficos
Publicado no:Open Biol
Main Authors: Alfieri, Claudio, Zhang, Suyang, Barford, David
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5717348/
https://ncbi.nlm.nih.gov/pubmed/29167309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.170204
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