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Coactivator functions in a stoichiometric complex with anaphase-promoting complex/cyclosome to mediate substrate recognition

The anaphase-promoting complex/cyclosome (APC/C) is a multisubunit E3 ligase required for ubiquitin-dependent proteolysis of cell-cycle-regulatory proteins, including mitotic cyclins and securin/Pds1. Regulation of APC/C activity and substrate recognition, mediated by the coactivators Cdc20 and Cdh1...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Passmore, Lori A, Barford, David
פורמט: Artigo
שפה:Inglês
יצא לאור: 2005
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC1369160/
https://ncbi.nlm.nih.gov/pubmed/16113654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400482
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