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Roles of the anaphase-promoting complex/cyclosome and of its activator Cdc20 in functional substrate binding
The anaphase-promoting complex/cyclosome (APC/C) is a multisubunit ubiquitin-protein ligase that targets for degradation cell-cycle regulatory proteins during exit from mitosis and in the G(1) phase of the cell cycle. The activity of APC/C in mitosis and in G(1) requires interaction with the activat...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1413726/ https://ncbi.nlm.nih.gov/pubmed/16455800 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0510695103 |
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