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Inhibitory factors associated with anaphase-promoting complex/cylosome in mitotic checkpoint

The mitotic (or spindle assembly) checkpoint system ensures accurate chromosome segregation by preventing anaphase initiation until all chromosomes are correctly attached to the mitotic spindle. It affects the activity of the anaphase-promoting complex/cyclosome (APC/C), a ubiquitin ligase that targ...

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Autors principals: Braunstein, Ilana, Miniowitz, Shirly, Moshe, Yakir, Hershko, Avram
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1829231/
https://ncbi.nlm.nih.gov/pubmed/17360335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0700523104
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