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Doc1 mediates the activity of the anaphase-promoting complex by contributing to substrate recognition

The anaphase-promoting complex (APC) is a multisubunit E3 ubiquitin ligase that targets specific cell cycle-related proteins for degradation, regulating progression from metaphase to anaphase and exit from mitosis. The APC is regulated by binding of the coactivator proteins Cdc20p and Cdh1p, and by...

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Detalhes bibliográficos
Main Authors: Passmore, Lori A., McCormack, Elizabeth A., Au, Shannon W.N., Paul, Angela, Willison, Keith R., Harper, J.Wade, Barford, David
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC145444/
https://ncbi.nlm.nih.gov/pubmed/12574115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg084
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