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Doc1 mediates the activity of the anaphase-promoting complex by contributing to substrate recognition
The anaphase-promoting complex (APC) is a multisubunit E3 ubiquitin ligase that targets specific cell cycle-related proteins for degradation, regulating progression from metaphase to anaphase and exit from mitosis. The APC is regulated by binding of the coactivator proteins Cdc20p and Cdh1p, and by...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2003
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC145444/ https://ncbi.nlm.nih.gov/pubmed/12574115 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg084 |
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