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Mechanisms for the temporal regulation of substrate ubiquitination by the anaphase-promoting complex/cyclosome

Abstract The anaphase-promoting complex/cyclosome (APC/C) is a multi-subunit, multifunctional ubiquitin ligase that controls the temporal degradation of numerous cell cycle regulatory proteins to direct the unidirectional cell cycle phases. Several different mechanisms contribute to ensure the corre...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Shivangee Bansal, Swati Tiwari
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2019-12-01
Schriftenreihe:Cell Division
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Online-Zugang:https://doi.org/10.1186/s13008-019-0057-5
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