Sumoylation promotes optimal APC/C activation and timely anaphase
The Anaphase Promoting Complex/Cyclosome (APC/C) is a ubiquitin E3 ligase that functions as the gatekeeper to mitotic exit. APC/C activity is controlled by an interplay of multiple pathways during mitosis, including the spindle assembly checkpoint (SAC), that are not yet fully understood. Here, we s...
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| Principais autores: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
eLife Sciences Publications Ltd
2018-03-01
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| Serier: | eLife |
| Fag: | |
| Online adgang: | https://elifesciences.org/articles/29539 |
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