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Atomic structure of the APC/C and its mechanism of protein ubiquitination
The anaphase-promoting complex (APC/C) is a multimeric RING E3 ubiquitin ligase that controls chromosome segregation and mitotic exit. Its regulation by coactivator subunits, phosphorylation, the mitotic checkpoint complex, and interphase inhibitor Emi1 ensures the correct order and timing of distin...
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| 出版年: | Nature |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4608048/ https://ncbi.nlm.nih.gov/pubmed/26083744 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature14471 |
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