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The Four Canonical TPR Subunits of Human APC/C Form Related Homo-Dimeric Structures and Stack in Parallel to Form a TPR Suprahelix()

The anaphase-promoting complex or cyclosome (APC/C) is a large E3 RING-cullin ubiquitin ligase composed of between 14 and 15 individual proteins. A striking feature of the APC/C is that only four proteins are involved in directly recognizing target proteins and catalyzing the assembly of a polyubiqu...

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Detalhes bibliográficos
Main Authors: Zhang, Ziguo, Chang, Leifu, Yang, Jing, Conin, Nora, Kulkarni, Kiran, Barford, David
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3898896/
https://ncbi.nlm.nih.gov/pubmed/23583778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2013.04.004
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