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The Spindle Assembly Checkpoint Is Not Essential for Viability of Human Cells with Genetically Lowered APC/C Activity
The anaphase-promoting complex/cyclosome (APC/C) and the spindle assembly checkpoint (SAC), which inhibits the APC/C, are essential determinants of mitotic timing and faithful division of genetic material. Activation of the APC/C is known to depend on two APC/C-interacting E2 ubiquitin-conjugating e...
Kaydedildi:
Yayımlandı: | Cell Rep |
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Asıl Yazarlar: | , , , , , |
Materyal Türü: | Artigo |
Dil: | Inglês |
Baskı/Yayın Bilgisi: |
Cell Press
2016
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Konular: | |
Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4785794/ https://ncbi.nlm.nih.gov/pubmed/26904940 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.01.060 |
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