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The transcription factor FBI-1 inhibits SAM68-mediated BCL-X alternative splicing and apoptosis

Alternative splicing (AS) is tightly coupled to transcription for the majority of human genes. However, how these two processes are linked is not well understood. Here, we unveil a direct role for the transcription factor FBI-1 in the regulation of AS. FBI-1 interacts with the splicing factor SAM68...

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Detalhes bibliográficos
Main Authors: Bielli, Pamela, Busà, Roberta, Di Stasi, Savino M, Munoz, Manuel J, Botti, Flavia, Kornblihtt, Alberto R, Sette, Claudio
Formato: Artigo
Idioma:Inglês
Publicado em: Backwell Publishing Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3989673/
https://ncbi.nlm.nih.gov/pubmed/24514149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/embr.201338241
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