c-MYC empowers transcription and productive splicing of the oncogenic splicing factor Sam68 in cancer

The splicing factor Sam68 is upregulated in many human cancers, including prostate cancer (PCa) where it promotes cell proliferation and survival. Nevertheless, in spite of its frequent upregulation in cancer, the mechanism(s) underlying its expression are largely unknown. Herein, bioinformatics ana...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Caggiano, Cinzia, Pieraccioli, Marco, Panzeri, Valentina, Sette, Claudio, Bielli, Pamela
Format: Artigo
Language:Inglês
Published: Oxford University Press 2019
Subjects:
Gene regulation, Chromatin and Epigenetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6614821/
https://ncbi.nlm.nih.gov/pubmed/31066450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz344
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