Sam68 marks the transcriptionally active stages of spermatogenesis and modulates alternative splicing in male germ cells

Sam68 plays an essential role in mouse spermatogenesis and male fertility. Herein, we report an interaction between Sam68 and the phosphorylated forms of the RNA polymerase II (RNAPII) in meiotic spermatocytes. RNase treatment decreased but did not abolish the interaction, consistently with in vitro...

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Hlavní autoři: Paronetto, Maria Paola, Messina, Valeria, Barchi, Marco, Geremia, Raffaele, Richard, Stéphane, Sette, Claudio
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2011
Témata:
Gene Regulation, Chromatin and Epigenetics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3130265/
https://ncbi.nlm.nih.gov/pubmed/21355037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr085
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