Sam68 marks the transcriptionally active stages of spermatogenesis and modulates alternative splicing in male germ cells

Sam68 plays an essential role in mouse spermatogenesis and male fertility. Herein, we report an interaction between Sam68 and the phosphorylated forms of the RNA polymerase II (RNAPII) in meiotic spermatocytes. RNase treatment decreased but did not abolish the interaction, consistently with in vitro...

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Bibliographic Details
Main Authors: Paronetto, Maria Paola, Messina, Valeria, Barchi, Marco, Geremia, Raffaele, Richard, Stéphane, Sette, Claudio
Format: Artigo
Language:Inglês
Published: Oxford University Press 2011
Subjects:
Gene Regulation, Chromatin and Epigenetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3130265/
https://ncbi.nlm.nih.gov/pubmed/21355037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr085
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