The transcription factor FBI-1 inhibits SAM68-mediated BCL-X alternative splicing and apoptosis

Alternative splicing (AS) is tightly coupled to transcription for the majority of human genes. However, how these two processes are linked is not well understood. Here, we unveil a direct role for the transcription factor FBI-1 in the regulation of AS. FBI-1 interacts with the splicing factor SAM68...

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Bibliographic Details
Main Authors: Bielli, Pamela, Busà, Roberta, Di Stasi, Savino M, Munoz, Manuel J, Botti, Flavia, Kornblihtt, Alberto R, Sette, Claudio
Format: Artigo
Language:Inglês
Published: Backwell Publishing Ltd 2014
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Scientific Reports
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3989673/
https://ncbi.nlm.nih.gov/pubmed/24514149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/embr.201338241
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