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The transcription factor FBI-1 inhibits SAM68-mediated BCL-X alternative splicing and apoptosis

Alternative splicing (AS) is tightly coupled to transcription for the majority of human genes. However, how these two processes are linked is not well understood. Here, we unveil a direct role for the transcription factor FBI-1 in the regulation of AS. FBI-1 interacts with the splicing factor SAM68...

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Bibliografski detalji
Glavni autori: Bielli, Pamela, Busà, Roberta, Di Stasi, Savino M, Munoz, Manuel J, Botti, Flavia, Kornblihtt, Alberto R, Sette, Claudio
Format: Artigo
Jezik:Inglês
Izdano: Backwell Publishing Ltd 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3989673/
https://ncbi.nlm.nih.gov/pubmed/24514149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/embr.201338241
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