JAK inhibitors suppress t(8;21) fusion protein-induced leukemia

Oncogenic mutations in components of the JAK/STAT pathway, including those in cytokine receptors and JAKs, lead to increased activity of downstream signaling and are frequently found in leukemia and other hematological disorders. Thus, small-molecule inhibitors of this pathway have been the focus of...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Lo, Miao-Chia, Peterson, Luke F., Yan, Ming, Cong, Xiuli, Hickman, Justin H., DeKelver, Russel C., Niewerth, Denise, Zhang, Dong-Er
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3987672/
https://ncbi.nlm.nih.gov/pubmed/23812420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2013.197
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky