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A pathway linking oxidative stress and the Ran GTPase system in progeria
Maintaining the Ran GTPase at a proper concentration in the nucleus is important for nucleocytoplasmic transport. Previously we found that nuclear levels of Ran are reduced in cells from patients with Hutchinson–Gilford progeria syndrome (HGPS), a disease caused by constitutive attachment of a mutan...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The American Society for Cell Biology
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3982987/ https://ncbi.nlm.nih.gov/pubmed/24523287 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E13-07-0430 |
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