Divergent roles of HDAC1 and HDAC2 in the regulation of epidermal development and tumorigenesis

The histone deacetylases HDAC1 and HDAC2 remove acetyl moieties from lysine residues of histones and other proteins and are important regulators of gene expression. By deleting different combinations of Hdac1 and Hdac2 alleles in the epidermis, we reveal a dosage-dependent effect of HDAC1/HDAC2 acti...

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Bibliografiske detaljer
Main Authors: Winter, Mircea, Moser, Mirjam A, Meunier, Dominique, Fischer, Carina, Machat, Georg, Mattes, Katharina, Lichtenberger, Beate M, Brunmeir, Reinhard, Weissmann, Simon, Murko, Christina, Humer, Christina, Meischel, Tina, Brosch, Gerald, Matthias, Patrick, Sibilia, Maria, Seiser, Christian
Format: Artigo
Sprog:Inglês
Udgivet: European Molecular Biology Organization 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3981143/
https://ncbi.nlm.nih.gov/pubmed/24240174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.243
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