Divergent roles of HDAC1 and HDAC2 in the regulation of epidermal development and tumorigenesis

The histone deacetylases HDAC1 and HDAC2 remove acetyl moieties from lysine residues of histones and other proteins and are important regulators of gene expression. By deleting different combinations of Hdac1 and Hdac2 alleles in the epidermis, we reveal a dosage-dependent effect of HDAC1/HDAC2 acti...

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Detalhes bibliográficos
Main Authors: Winter, Mircea, Moser, Mirjam A, Meunier, Dominique, Fischer, Carina, Machat, Georg, Mattes, Katharina, Lichtenberger, Beate M, Brunmeir, Reinhard, Weissmann, Simon, Murko, Christina, Humer, Christina, Meischel, Tina, Brosch, Gerald, Matthias, Patrick, Sibilia, Maria, Seiser, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: European Molecular Biology Organization 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3981143/
https://ncbi.nlm.nih.gov/pubmed/24240174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.243
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