Divergent roles of HDAC1 and HDAC2 in the regulation of epidermal development and tumorigenesis

The histone deacetylases HDAC1 and HDAC2 remove acetyl moieties from lysine residues of histones and other proteins and are important regulators of gene expression. By deleting different combinations of Hdac1 and Hdac2 alleles in the epidermis, we reveal a dosage-dependent effect of HDAC1/HDAC2 acti...

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Hlavní autoři: Winter, Mircea, Moser, Mirjam A, Meunier, Dominique, Fischer, Carina, Machat, Georg, Mattes, Katharina, Lichtenberger, Beate M, Brunmeir, Reinhard, Weissmann, Simon, Murko, Christina, Humer, Christina, Meischel, Tina, Brosch, Gerald, Matthias, Patrick, Sibilia, Maria, Seiser, Christian
Médium: Artigo
Jazyk:Inglês
Vydáno: European Molecular Biology Organization 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3981143/
https://ncbi.nlm.nih.gov/pubmed/24240174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.243
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