T cells translate individual, quantal activation into collective, analog cytokine responses via time-integrated feedbacks

Variability within isogenic T cell populations yields heterogeneous ‘local’ signaling responses to shared antigenic stimuli, but responding clones may communicate ‘global’ antigen load through paracrine messengers, such as cytokines. Such coordination of individual cell responses within multicellula...

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Detaylı Bibliyografya
Asıl Yazarlar: Tkach, Karen E, Barik, Debashis, Voisinne, Guillaume, Malandro, Nicole, Hathorn, Matthew M, Cotari, Jesse W, Vogel, Robert, Merghoub, Taha, Wolchok, Jedd, Krichevsky, Oleg, Altan-Bonnet, Grégoire
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: eLife Sciences Publications, Ltd 2014
Konular:
Biophysics and Structural Biology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3980879/
https://ncbi.nlm.nih.gov/pubmed/24719192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.01944
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