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Diversity training for signal transduction: leveraging cell-to-cell variability to dissect cellular signaling, differentiation and death
Populations of “identical” cells are rarely truly identical. Even when in the same state of differentiation, isogenic cells may vary in expression of key signaling regulators, activate signal transduction at different thresholds, and consequently respond heterogeneously to a given stimulus. Here, we...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3863640/ https://ncbi.nlm.nih.gov/pubmed/23747193 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.copbio.2013.05.002 |
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