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Diversity training for signal transduction: leveraging cell-to-cell variability to dissect cellular signaling, differentiation and death
Populations of “identical” cells are rarely truly identical. Even when in the same state of differentiation, isogenic cells may vary in expression of key signaling regulators, activate signal transduction at different thresholds, and consequently respond heterogeneously to a given stimulus. Here, we...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3863640/ https://ncbi.nlm.nih.gov/pubmed/23747193 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.copbio.2013.05.002 |
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