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Dissecting common γ chain cytokine family signaling in T cells using cell-to-cell variability analysis
Natural variability in abundance of signaling regulators can lead to divergence in cell fate, even within genetically identical cells sharing a common differentiation state. To leverage this observation, we introduce cell-to-cell variability analysis (CCVA), an experimental and computational methodo...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3896501/ https://ncbi.nlm.nih.gov/pubmed/23482665 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2003240 |
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