Myocardial Infarction-induced N-terminal Fragment of Cardiac Myosin-binding Protein C (cMyBP-C) Impairs Myofilament Function in Human Myocardium

Myocardial infarction (MI) is associated with depressed cardiac contractile function and progression to heart failure. Cardiac myosin-binding protein C, a cardiac-specific myofilament protein, is proteolyzed post-MI in humans, which results in an N-terminal fragment, C0-C1f. The presence of C0-C1f i...

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Bibliografski detalji
Glavni autori: Witayavanitkul, Namthip, Ait Mou, Younss, Kuster, Diederik W. D., Khairallah, Ramzi J., Sarkey, Jason, Govindan, Suresh, Chen, Xin, Ge, Ying, Rajan, Sudarsan, Wieczorek, David F., Irving, Thomas, Westfall, Margaret V., de Tombe, Pieter P., Sadayappan, Sakthivel
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2014
Teme:
Molecular Bases of Disease
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979389/
https://ncbi.nlm.nih.gov/pubmed/24509847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.541128
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