Phosphorylation of cMyBP-C Affects Contractile Mechanisms in a Site-specific Manner

Cardiac myosin binding protein-C (cMyBP-C) is a cardiac-specific, thick-filament regulatory protein that is differentially phosphorylated at Ser(273), Ser(282), and Ser(302) by various kinases and modulates contraction. In this study, phosphorylation-site-specific effects of cMyBP-C on myocardial co...

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Bibliographic Details
Main Authors: Wang, Li, Ji, Xiang, Barefield, David, Sadayappan, Sakthivel, Kawai, Masakata
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2014
Subjects:
Molecular Machines, Motors and Nanoscale Biophysics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4026776/
https://ncbi.nlm.nih.gov/pubmed/24606935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.01.029
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