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Evidence That Bank Vole PrP Is a Universal Acceptor for Prions

Bank voles are uniquely susceptible to a wide range of prion strains isolated from many different species. To determine if this enhanced susceptibility to interspecies prion transmission is encoded within the sequence of the bank vole prion protein (BVPrP), we inoculated Tg(M109) and Tg(I109) mice,...

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Hlavní autoři: Watts, Joel C., Giles, Kurt, Patel, Smita, Oehler, Abby, DeArmond, Stephen J., Prusiner, Stanley B.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3974871/
https://ncbi.nlm.nih.gov/pubmed/24699458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003990
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