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Evidence That Bank Vole PrP Is a Universal Acceptor for Prions

Bank voles are uniquely susceptible to a wide range of prion strains isolated from many different species. To determine if this enhanced susceptibility to interspecies prion transmission is encoded within the sequence of the bank vole prion protein (BVPrP), we inoculated Tg(M109) and Tg(I109) mice,...

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Bibliografiske detaljer
Main Authors: Watts, Joel C., Giles, Kurt, Patel, Smita, Oehler, Abby, DeArmond, Stephen J., Prusiner, Stanley B.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3974871/
https://ncbi.nlm.nih.gov/pubmed/24699458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003990
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